Helicobacter pylori. Helicobacter pylori [H.pylori]
Conditions
Interventions
Intervention 1: Intervention group: Standard treatment (omeprazole capsules produced by Iran Darou Company (20 mg every 12 hours), amoxicillin capsules 500 ml produced by Al-Hawi Pharmaceutical Compan
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with functional dyspepsia or gastroduodenal ulcer who have an indication for eradicating Helicobacter pylori infection Confirmation of Helicobacter pylori infection through pathology results obtained from endoscopy or positive stool antigen test for Helicobacter pylori Minimum age 18 years
Exclusion criteria
Exclusion criteria: Previous eradication of Helicobacter pylori Use of antibiotics, PPIs, or chemotherapeutic agents within the 4 weeks prior to the study Patients with a history of gastrectomy or complicated peptic ulcer Pregnant and nursing women established.Patients with recompensated kidney and heart failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication of Helicobacter pylori infection. Timepoint: After the end of the antibiotic treatment period, omeprazole treatment was continued for 4 weeks, and eradication of the infection was measured two weeks after omeprazole was discontinued. Method of measurement: Fecal antigen test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects of treatment (bitter taste in the mouth, black stool, diarrhea, nausea, vomiting). Timepoint: After the treatment period. Method of measurement: Patient self-expression. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Sadeghi
Kashan University of Medical Sciences
Outcome results
None listed