Skip to content

Inhaled magnesium sulfate in COPD (Chronic Obstructive Pulmonary Diseases)

The effect of inhaled magnesium sulfate on the duration of hospitalization and spirometry indicators in patients with chronic obstructive pulmonary disease

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250528065953N1
Enrollment
384
Registered
2025-07-21
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive pulmonary Disease Exacerbation. Chronic obstructive pulmonary disease with (acute) exacerbation

Interventions

Intervention 1: Intervention group: The other 118 patients, in addition to receiving standard treatment, will be administered ready-to-use vials of inhaled magnesium sulfate via nebulizer at a dose of

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Individuals with a history of COPD who have been hospitalized due to acute exacerbations Individuals who have been diagnosed with COPD through spirometry Individuals who have an FEV1 of 80% or lower and/or an FEV1/FVC ratio of less than 70%.

Exclusion criteria

Exclusion criteria: Pneumonia Malignancy CHF (Congestive Heart Failure) Astham Hospitalization for a reason other than chronic obstructive pulmonary disease (COPD) exacerbation.

Design outcomes

Primary

MeasureTime frame
Length of Hospital stay. Timepoint: Once, at the time of the patient's discharge. Method of measurement: Patient medical records.;FEV1/FVC. Timepoint: Baseline and after 5 days. Method of measurement: with Spirometry.

Secondary

MeasureTime frame
Admission Interval. Timepoint: Up to 6 month after the primary discharge. Method of measurement: Based on the patient's medical record.;GOLD. Timepoint: On each admission time. Method of measurement: Based on Spirometry and GOLD criteria.;FEV1. Timepoint: Baseline (from the admission) and 5 days after admission. Method of measurement: Spirometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Dasdar

Kashan University of Medical Sciences

Dasdar-A@kaums.ac.ir+98 31 5558 9347

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026