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Investigating the effectiveness of misoprostol alone compared to misoprostol and tractional catheter for abortion in missed abortions in the second trimester.

Investigating the effectiveness of misoprostol alone compared to misoprostol and tractional catheter for missed abortions in the second trimester in two groups.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250526065915N1
Enrollment
66
Registered
2025-06-09
Start date
2025-06-20
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Missed abortion. Missed abortion

Interventions

Intervention 1: Intervention group: Using misoprostole alone to complete expulsion. Intervention 2: Intervention group: Using misoprostole and foley catheter to complete expulsion.

Sponsors

Karaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Women in their second trimester of pregnancy who have experienced a missed abortion and are candidates for medical termination of pregnancy.

Exclusion criteria

Exclusion criteria: Women who choose alternative methods for managing abortion (expectant or surgical) Nulliparous women Those diagnosed with incomplete abortion Life-threatening bleeding Premature rupture of membranes (PPROM) Contraindications to misoprostol use such as asthma or coronary artery disease and renal failure Known coagulopathies or a history of chronic adrenal insufficiency Ruptured membranes Infection Placenta previa Polyhydramnios Women who decline to participate in the study.

Design outcomes

Primary

MeasureTime frame
Complete expulsion. Timepoint: From the begining of medical treatment untill 24 hours. Method of measurement: Control Sonography.

Secondary

MeasureTime frame
Pain. Timepoint: From the begining of medical treatment untill 24 hours. Method of measurement: Pain based on VAS score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Nematollahzadeh

Karaj University of Medical Sciences

zahranematollahi1998@gmail.com+98 912 006 1539

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026