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Comparing the efficacy of split-dose sodium picosulfate/ mangnesium citrate (SPMC) regimen versus polyethylene glycol (PEG) for colonoscopy preparation in outpatients: A Randomized Clinical Traial

Comparing the efficacy of split-dose sodium picosulfate/ mangnesium citrate (SPMC) regimen versus polyethylene glycol (PEG) for colonoscopy preparation in outpatients: A Randomized Clinical Traial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250526065902N1
Enrollment
144
Registered
2025-07-06
Start date
2025-07-23
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonoscopy to check for colon cancer, polyps, and adenomas.

Interventions

Intervention group: Two groups of 72 people. The first group (Nonapick drug) was given one sachet of Nonapick (containing 16 grams of SPMC) to prepare a 150 ml solution at 2, 5 and 8 pm on the day bef

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Adults aged 15 to 65 years who are seen on an outpatient basis for screening for colon cancer, constipation, abdominal pain, weight loss, and anemia.

Exclusion criteria

Exclusion criteria: Includes severe chronic constipation (as defined by spontaneous bowel movements less than 3 times per week), suspected intestinal perforation or obstruction, history of colon or upper gastrointestinal surgery (gastrectomy, gastric bypass), pregnancy or lactation, mental disorders, renal failure (serum creatinine greater than 1.5 times the upper limit of normal, creatinine clearance less than 30 mL/min), active inflammatory bowel disease (acute/severe/uncontrolled), congestive heart failure (class II-IV), uncontrolled hypertension, or allergies

Design outcomes

Primary

MeasureTime frame
Colon cleansing based on the Boston Bowel Preparation Scale (BBPS) scoring standard. Timepoint: During colonoscopy. Method of measurement: The Olympus CV-190 Colonoscopy Device.

Secondary

MeasureTime frame
Includes tolerability, taste of the medication, ease of use, rate of adenoma detection (ADR), polyps, colon cancer, and side effects, and willingness to reuse. Timepoint: before and during of Colonoscopy. Method of measurement: Colonoscopy device and questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAref shiar

Babol University of Medical Sciences

Arefshiar74@gmail.com+98 11 3219 9592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026