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Investigating the effect of administering ondansetron on the need for sedation and patient comfort before esophagus echocardiography

Investigating the effect of administering ondansetron on the need for sedation and patient comfort before esophagus echocardiography

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250525065885N1
Enrollment
56
Registered
2025-06-17
Start date
2025-06-22
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients requiring transesophageal echocardiography (TEE). Patients requiring transesophageal echocardiography (TEE)

Interventions

Intervention 1: Intervention group: Patients who were candidates for TEE received 4 mg of ondansetron intravenously, 5 to 10 minutes before TEE. Intervention 2: Control group: TEE candidate patients w

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: All people who have indications for esophageal echocardiography They consent to enter the project. Age between 18 years and 70 years

Exclusion criteria

Exclusion criteria: Emergency examinations pregnancy Mechanical ventilation Upper gastrointestinal endoscopy findings include: Esophageal Perforation, Strictures, Tumors, or Diverticula . Hiatal Hernia . Esophageal Varices Active Upper Gastrointestinal Bleeding . Recent Esophageal or Gastric Surgery Cervical Spine Instability or Arthritis Coagulopathy Inability to Protect the Airway

Design outcomes

Primary

MeasureTime frame
Aldert and Krolik Postanesthesia Recovery Score as a Measure of Patient Comfort. Timepoint: During the procedure and afterwards until discharge. Method of measurement: Checklist.

Secondary

MeasureTime frame
Percutaneous arterial oxygen saturation level. Timepoint: During the entire procedure and afterwards until discharge. Method of measurement: Pulse oximetry.;Information on additional doses of midazolam. Timepoint: During the entire procedure and afterwards until discharge. Method of measurement: Checklist.;Blood pressure. Timepoint: During the entire procedure and afterwards until discharge. Method of measurement: Blood pressure measuring device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Sara afshar

Mashhad University of Medical Sciences

Afshars@mum.ac.ir+98 51 3854 3031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026