Studying the effect of probiotic supplements on In Vitro Fertilization (IVF) success in infertile women

The effect of probiotic supplements on In Vitro Fertilization (IVF) success in infertile women

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250524065871N1

Enrollment

180

Registered

2025-05-29

Start date

2025-06-22

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: This group receives one Lactofem probiotic tablet daily for 2 weeks before embryo transfer. Intervention 2: Control group: This group does not receive any probiotic

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Infertile women (including women with primary or secondary infertility) who are planning to undergo In Vitro Fertilization (IVF). Age 18 to 40 years Body mass index (BMI) between 18.5 and 30

Exclusion criteria

Exclusion criteria: Chronic illnesses or digestive problems that require special treatment Pregnancy or breastfeeding Having acute pancreatitis Certain medications that may affect the outcome of IVF or the effectiveness of probiotics Sensitivity to probiotics or components in Lactofem

Design outcomes

Primary

Measure	Time frame
IVF success. Timepoint: Pregnancy blood test 2 weeks after embryo transfer. Method of measurement: Pregnancy blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoraya Servatian

Qazvin University of Medical Sciences

nedasrvtn@gmail.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026