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“Evaluation of chitosan gel in periodontal treatment”

Clinical and radiographic evaluation of the effect of chitosan-containing gel in the treatment of periodontal intraosseous defects

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250524065870N1
Enrollment
26
Registered
2025-06-03
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Three-walled or two-walled combined interdental intraosseous defects in maxillary and mandibular premolars or molars.

Interventions

Intervention 1: “Intervention group”: 10% chitosan gel
C6H11NO4
Iran Chitosan Company
Once during surgery, flaps are placed with a syringe in the proximal area of ??teeth that have bone defects and does not require extraction. Intervention 2: Control group: Placebo gel is placed once

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients with moderate chronic periodontitis involving three-walled or two-walled combined intraosseous lesions in the maxillary or mandibular first and second premolars and molars

Exclusion criteria

Exclusion criteria: Having a systemic disease Need for prophylactic antibiotics Use of medications that interfere with the improvement of periodontal disease smoking Teeth with Grade 2 mobility Periapical pathology Coagulation problems

Design outcomes

Primary

MeasureTime frame
Clinical attachment loss more than 5 mm. Timepoint: Measurements of Pocket Probing Depth, Clinical Attachment Loss around the tooth, degree of Gingival Recession, and degree of Gingival Index are taken around each tooth at baseline (before surgery) and then 6 months after surgery. Method of measurement: Pocket Probing Depth, Clinical Attachment Loss around the tooth, and the extent of Gingival Recession are measured by Periodontal Probe; Gingival Index is measured by visual observation of bleeding, and the degree of bone change is measured by Subtraction Radiography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Jenabian

Babol University of Medical Sciences

niloofarjenabian@yahoo.com+98 11 3219 9592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026