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The effect of vitamin C supplementation, alone and in combination with zinc, on improving hearing loss

Comparing the Effects of Vitamin C Supplementation Alone versus Combined with Zinc on Noise-Induced Hearing Loss Recovery in Industrial Workers

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250519065804N1
Enrollment
105
Registered
2025-09-07
Start date
2025-07-22
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Noise-induced hearing loss.

Interventions

Intervention 1: intervention groups: Participants were assigned to two intervention groups.Intervention Group 1 (Vitamin C + Zinc placebo): Participants in this group received one 1000 mg vitamin C ta

Sponsors

Saveh University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age: Participants must be between 20 and 50 years old. Work Experience: Participants must have at least 3 years of work experience in a noisy environment (above 95 dB). Hearing Loss: Participants should have a mild degree of occupational hearing loss. Willingness to Participate: Workers must be willing and prepared to participate in the study and follow instructions. Physical Health Status: Workers must be in good physical health. No Second Job: Participants should not have a second job.

Exclusion criteria

Exclusion criteria: Recent Supplement Use: Participants who have consumed Vitamin C, zinc supplements, or any supplement containing these compounds for any reason within the past two months are excluded. Hearing Health: Participants must not have any per-existing hearing conditions such as congenital hearing loss, chronic ear infections, or other hearing disorders. Medical History: Participants must not have a history of kidney stones, thalassemia (minor or major), advanced liver diseases (cirrhosis, necrosis), advanced cardiovascular problems (heart failure), or cancer. obacco, Alcohol, and Ototoxic Drug Use: Participants must not be current users of tobacco (cigarettes) or alcohol.

Design outcomes

Primary

MeasureTime frame
Hearing loss. Timepoint: Measurement of hearing loss before and after the intervention. Method of measurement: Audiometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMilad Abbasi

Saveh University of Medical Sciences

milad8285@gmail.com+98 86 4850 3202

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026