Effect of PRP on surgical scar quality after laparoscopic gallbladder removal

Effect of Platelet-Rich Plasma (PRP) on Port Site Scar Quality Following Laparoscopic Cholecystectomy: A Randomized Controlled Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250519065801N1

Enrollment

Registered

2026-05-03

Start date

2026-05-22

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing laparoscopic cholecystectomy for symptomatic cholelithiasis. Cholelithiasis

Interventions

Intervention 1: Intervention group : Surgical port sites receiving platelet-rich plasma (PRP) infiltration at the time of skin closure. The intervention is applied to port sites preselected through ra

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients undergoing laparoscopic cholecystectomy surgery.

Exclusion criteria

Exclusion criteria: History of allergic reaction to PRP or blood products Intraoperative conversion to open surgery Withdrawal of consent at any time

Design outcomes

Primary

Measure	Time frame
Quality of surgical port site scars following laparoscopic cholecystectomy. Timepoint: At 1 , 3 and 6 month postoperatively. Method of measurement: Scar quality will be assessed using the Vancouver Scar Scale (VSS) and, if feasible, the Patient and Observer Scar Assessment Scale (POSAS), by an assessor blinded to group allocation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammad Yousefi

Shahid Beheshti University of Medical Sciences

Yousefi.m13@gmail.com+98 21 2201 4976

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026