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Examining the results of the use of topical antibiotic cocktail in the prevention of infection after bilateral hip joint replacement in patients referred to hospital

Examining the results of the use of topical antibiotic cocktail in the prevention of infection after bilateral hip joint replacement in patients referred to Hospital

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250518065782N1
Enrollment
40
Registered
2025-05-21
Start date
2025-05-18
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection prevention after bilateral hip replacement. Infection and inflammatory reaction due to internal joint prosthesis

Interventions

Intervention group: Topical antibiotic cocktail (cefazolin, clindamycin, gentamicin, vancomycin) applied on Surgicel and placed inside one hip joint during surgery to prevent postoperative infection..

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who are candidates for bilateral total hip arthroplasty (THA). Referral to Erfan-Niyayesh, Erfan-Saadat Abad, or Farhikhtegan Hospitals in the year 2025 Obtained informed consent for participation in the study.

Exclusion criteria

Exclusion criteria: History of prior hip surgery. Incomplete or missing patient records

Design outcomes

Primary

MeasureTime frame
Incidence of superficial and deep infections up to 3–4 months after bilateral hip replacement surgery. Timepoint: 3 and 4 months post-surgery. Method of measurement: Infection occurrence assessed by clinical examination, laboratory tests (e.g., cultures), and hospital records during 3 to 4 months post-surgery.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Soheil Ghafari Alooji

Islamic Azad University

Dr.ghafari2020@gmail.com00 98 33890360

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026