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Comparison of the efficacy of lidocaine infiltrative anesthesia (local anesthesia in a small area) and articaine in molar implant surgery of the mandible (lower jaw): a clinical trial

Comparison of the Effectiveness of Articaine versus lidocaine infiltration anesthesia on pain inensity in mandibular molars implant surgery: a randomized controlled trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250514065725N1
Enrollment
62
Registered
2025-06-06
Start date
2025-05-22
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Edentulous in the molar area of the mandible.

Interventions

Intervention 1: Intervention group: Lidocaine, Name of the substance used: Persocaine E, Chemical composition per ml: Lidocaine hydrochloride 20 mg and epinephrine 12.5 micrograms, Dosage: 3.6 mg (two

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients who require implant treatment in this area due to the loss of mandibular molar teeth. Patients with systemic conditions ASA class one and two. Patients aged 18-60 years non-smoking patients The implant placement area should have healed and there should be no need for bone reconstruction. At least 3 months must have passed since the extraction treatment. There should be no unusual presence in the graphical representation of the Lucency or opacity region.

Exclusion criteria

Exclusion criteria: Prohibition of the use of epinephrine with a preservative The use of narcotics, sedatives, NSAIDs, psychoactive substances, and anything that alters the patient's perception of pain. Advanced surgical needs Non-healthiness of the pulp of the adjacent teeth Need for remote flap Patients who are unwilling to sign the consent form. The patient expresses pain during soft tissue manipulation and requires the injection of more than two carpules of anaesthetic. Prolongation of the surgical process (more than 1 hour)

Design outcomes

Primary

MeasureTime frame
Pain intensity score. Timepoint: 1 and 4 hours after the surgery is completed. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZohreh Afshari

Esfahan University of Medical Sciences

zeynep13802001@gmail.com+98 31 3792 5538

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026