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The Effect of Oral and Vaginal Misoprostol on the Duration of first Labor Induction

The Effect of Oral Vs Vaginal Misoprostol on The Duration of Induction of First Labor

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250513065720N1
Enrollment
70
Registered
2025-10-20
Start date
2025-08-22
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childbirth. Other specified complications of labor and delivery

Interventions

Intervention 1: Intervention Group 1: Misoprostol 50 Microgram Tablets (Mizotec Tablets, Abu Rayhan Pharmaceutical Company) Orally Every 6 Hours Until Reaching a Bishop Score of more than 8 or a Maxim

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Term Pregnancy (Less than or Equal to 37 weeks of Gestation) with a Singleton is Estimated based on the LMP Criterion (if Regularly and Reliably Confirmed by a Specialist Physician) or Ultrasound. Bishop Score Less than or Equal to 6 Cephalic Presentation of the fetus Having an Intact Membrane Reactivity of the Non-Stress Test Amniotic fluid volume less than 5 Estimated Fetal Weight less than 4000 Grams First Birth of a Pregnant Mother

Exclusion criteria

Exclusion criteria: Pregnant women with contraindications to vaginal delivery Chorioamnionitis HIV positivity Previous uterine surgery Abnormal fetal heartbeat pattern Vaginal Bleeding and Women with Known Hypersensitivity to Misoprostol or Prostaglandin Analogues

Design outcomes

Primary

MeasureTime frame
Time from Intervention to Natural Birth. Timepoint: From the time of the first dose of Misoprostol to the delivery of the Baby. Method of measurement: Clinical Record, Physical Examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Toghrali

Kerman University of Medical Sciences

www.dr.maryamtoghroli@gmail.com+98 34 3132 8000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026