the effect of Daflon oral drug in the treatment of grade 1 and 2 hemorrhoids

Evaluation of the effect of Daflon oral drug compared to palliative drugs in the treatment of grade 1 and 2 hemorrhoids

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250512065701N1

Enrollment

114

Registered

2025-09-14

Start date

2025-06-22

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemorrhoids. First degree hemorrhoids

Interventions

Intervention 1: The intervention group will receive a 500 mg Daflon tablet (Amin Pharmaceutical Company) every 12 hours and a 500 mg acetaminophen tablet daily for one month, along with painkillers (

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years having grade 1 and 2 hemorrhoids willingness to participate in the study

Exclusion criteria

Exclusion criteria: patients who are candidates for immediate surgery cancer active inflammatory bowel disease a history of anal or rectal surgery severe or uncontrolled systemic disease pregnant or breastfeeding

Design outcomes

Primary

Measure	Time frame
Recovery time. Timepoint: before and 1 month after the intervention. Method of measurement: Time interval between intervention and recovery in days.;Wound size. Timepoint: before and 1 month after the intervention. Method of measurement: Hemorrhoid ulcer size according to Calibrated Probe.;Amount of bleeding. Timepoint: before and 1 month after the intervention. Method of measurement: Amount of blood lost during a month in cc by gravimetric method.;Need for surgery. Timepoint: One month after the intervention. Method of measurement: The need for surgery based on the decision of a specialist doctor.	—

Measure

Time frame

Recovery time. Timepoint: before and 1 month after the intervention. Method of measurement: Time interval between intervention and recovery in days.;Wound size. Timepoint: before and 1 month after the intervention. Method of measurement: Hemorrhoid ulcer size according to Calibrated Probe.;Amount of bleeding. Timepoint: before and 1 month after the intervention. Method of measurement: Amount of blood lost during a month in cc by gravimetric method.;Need for surgery. Timepoint: One month after the intervention. Method of measurement: The need for surgery based on the decision of a specialist doctor.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojtaba Shurmij

Tehran University of Medical Sciences

M.shurmij@gmail.com+98 21 6601 5493

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026