Skip to content

Comparison of Different Types of Bioceramic Sealers on Post-Treatment Pain in Symptomatic Teeth

Comparative analysis of postoperative pain in symptomatic irreversible pulpitis teeth following single cone obturation Using three Different Sealers: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250510065680N1
Enrollment
75
Registered
2025-07-01
Start date
2025-08-23
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comparison of post endodontic pain with various sealers.

Interventions

Intervention 1: Intervention group 1 : Endoseal Tcs Sealer. Intervention 2: Intervention group 2: Neosealer bioceramic sealer. Intervention 3: Control group: AH plus sealer.

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age Range of Patients: Between 18 and 50 years. Adequate Oral and Dental Hygiene. Prolonged Positive Response to Cold and Electric Pulp Tester. Patients Diagnosed with Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis in the First or Second Molar of the Maxilla or Mandible. Pulp Exposure During Caries Removal Accompanied by Severe and Thick Hemorrhage. Patients Without Radiographic Evidence of Periapical Lesions. Teeth with Restorative Potential. Patients Without Periodontal Problems.

Exclusion criteria

Exclusion criteria: Teeth with crowns that cannot be restored. presence of endo-perio lesion teeth with endodontic lesion Teeth with internal or external resorption calcified teeth Patients with systemic diseases and migraines classified as ASA II or higher Teeth with over or under obturation to 2mm from the apex Patients taking anti-anxiety medications. Cases with procedural duration exceeding two hours. Individuals allergic to materials used in root canal treatment, including local anesthetics.

Design outcomes

Primary

MeasureTime frame
Post endodontic therapy pain. Timepoint: First 8 hours post treatment, 24 h after, 48 h after. Method of measurement: Visual analog scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayeh Majidi

Tehran University of Medical Sciences

dr.somaiemajidi@yahoo.com+98 21 4279 4000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026