Formulation of syrup based on bee-collected pollen extract and investigation of its effects on patients with polycystic ovary syndrome

Formulation of syrup based on bee-collected pollen extract and investigation of its effects on biochemical, hormonal, and anthropometric indices in patients with polycystic ovary syndrome (PCOS): A clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250509065667N1

Enrollment

Registered

2025-06-01

Start date

2025-06-04

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome. Sclerocystic ovary syndrome

Interventions

Intervention 1: Women aged 15 to 49 (women and girls of reproductive age) with polycystic ovary syndrome who were referred to a private gynecologist and obstetrician office in Khorramabad city who wer

Eligibility

Sex/Gender

Female

Age

15 Years to 49 Years

Inclusion criteria

Inclusion criteria: Suffering from polycystic ovary syndrome Women aged 15 to 49 (women and girls of reproductive age) Resident of Khorramabad city

Exclusion criteria

Exclusion criteria: Consumption of vitamins (except vitamin D), hormonal contraceptives, minerals, traditional medicine, dietary supplements, lipid-lowering drugs, and omega-3 during the study and 3 months before the intervention Having other metabolic diseases such as diabetes and androgenic disorders such as congenital adrenal hyperplasia (CAH) or androgen-producing glands, thyroid gland diseases, Cushing's syndrome Pregnancy or breastfeeding Previous surgery on one or both ovaries Smoking and alcohol consumption

Design outcomes

Primary

Measure	Time frame
Fasting Blood Sugar. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Insulin. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Total Cholesterol. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Triglyceride. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Low Density Lipoprotein Cholesterol. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;High Density Lipoprotein Cholesterol. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;C-Reactive Protein. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Testosterone. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;LH. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;FSH. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Estradiol. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Body Mass Index. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Using scales and a tape measure and plugging into the formula.;Waist circumference. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Usin	—

Measure

Time frame

Fasting Blood Sugar. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Insulin. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Total Cholesterol. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Triglyceride. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Low Density Lipoprotein Cholesterol. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;High Density Lipoprotein Cholesterol. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;C-Reactive Protein. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Testosterone. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;LH. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;FSH. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Estradiol. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Serum level.;Body Mass Index. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Using scales and a tape measure and plugging into the formula.;Waist circumference. Timepoint: Before the start of the intervention and 12 weeks after the start of supplementation. Method of measurement: Usin

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKeyheneh Kohi

Khoram-Abad University of Medical Sciences

kohikeyhaneh@gmail.com+98 66 3340 8176

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026