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Laparoscopic vs. Open Appendectomy: Surgical Site Infection Study

Comparison of Laparoscopic Appendectomy Vs Open Appendectomy concerning Early Surgical Site Infection Incidence, Single-Blinded Parallel-Group, Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250507065635N1
Enrollment
162
Registered
2025-10-01
Start date
2025-08-23
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute appendicitis. Unspecified acute appendicitis

Interventions

Intervention 1: Control group: Open appendectomy (OA) performed under general anesthesia through a right lower quadrant abdominal incision using the standard open surgical technique. Skin closure is p

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 65 Years

Inclusion criteria

Inclusion criteria: All patients with acute appendicitis and an Alvarado score greater than five will be included in the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Surgical site infection (SSI). Postoperative days 1, 2, 3, 4, 7, and 14 will be considered as the primary time points for outcome assessment. At these intervals, the surgical wound will be evaluated in terms of its appearance (e.g., potential discharge), blood tests (e.g., leukocyte count), and the presence of intra-abdominal abscesses using ultrasound imaging. Timepoint: Surgical site infection (SSI). Postoperative days 1, 2, 3, 4, 7, and 14 will be considered as the primary time points for outcome assessment. Method of measurement: The surgical wound will be evaluated in terms of its appearance (e.g., potential discharge), blood tests (e.g., leukocyte count), and the presence of intra-abdominal abscesses using ultrasound imaging.

Secondary

MeasureTime frame
Surgery duration. Timepoint: By a digital clock by minute, and then entering it into a checklist. Method of measurement: Once during an appendectomy for each person.;Postoperative pain score. Timepoint: For each person, 6, 2, 12, and 24 hours after the operation. Method of measurement: Visual Analog Scale.;Frequency of use of housing until 48 hours after the operation. Timepoint: until 48 hours after the operation. Method of measurement: Using the patient record.;Start consuming food. Timepoint: Recording the time of first intake of oral fluids, recording the time of starting a soft diet or light solid food, and recording the time of complete return to a normal diet after surgery. Method of measurement: Recording the time of first intake of oral fluids, recording the time of starting a soft diet or light solid food, and recording the time of complete return to a normal diet after surgery.;Improve bowel movement. Timepoint: Recording the time of the first gas, recording the time of the first bowel movement, recording the time of hearing bowel sounds, and recording the time of food tolerance without nausea/vomiting. Method of measurement: Recording the time of the first gas, recording the time of the first bowel movement, recording the time of hearing bowel sounds, and recording the time of food tolerance without nausea/vomiting.;Recovery of physical activity. Timepoint: Record the time when you do not need help to walk or go to the bathroom. Method of measurement: Record the time when you do not need help to walk or go to the bathroom.;Length of hospital stay after surgery. Timepoint: Length of hospital stay after surgery. Method of measurement: Length of hospital stay by day and then recorded in the checklist.;Changes in white blood cells and CRP levels after surgery. Timepoint: Twice: once 24 hours after surgery and once 5 days after surgery. Method of measurement: White blood cell count and C-reactive protein level.;Postoperative quality of life. Timepoint: 7 days

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Doost Mohammadi

Kerman University of Medical Sciences

f.doostmohammadi2@gmail.com+98 34 3244 1553

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026