Uremic Pruritus. Other pruritus
Conditions
Interventions
Intervention 1: Intervention group: 75 hemodialysis patients of Shahid Mohammadi Hospital, Bandar Abbas, who suffer from Pruritus and meet the inclusion criteria, will be randomly assigned to the stud
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
16 Years to 80 Years
Inclusion criteria
Inclusion criteria: Diagnosis of End-Stage Renal Disease (ESRD) Hospitalization and undergoing hemodialysis Willingness to participate in the study (informed consent)
Exclusion criteria
Exclusion criteria: Patients with hepatic failure Hyperthyroidism Angle-closure glaucoma Heart block Decompensated heart failure Hypotension History of hypersensitivity to gabapentin or doxepin Uncontrolled psychiatric disorders Myocardial infarction within the past three months Epilepsy, history of even a single seizure, or pregnancy Patients with psoriasis, atopic dermatitis, or any other condition that could explain pruritus Contraindications to Gabapentin include: Renal impairment; Psychiatric or mood disorders such as depression and suicidal ideation; Substance or alcohol abuse; Respiratory disorders. Contraindications to Doxepin: Bleeding disorders; Recent myocardial infarction; Urinary disorders such as prostatic hypertrophy; Personal or family history of angle-closure glaucoma; Personal or family history of psychiatric or mood disorders (e.g., bipolar disorder, psychosis); Family history of suicide; Seizures or conditions that may increase the risk of seizures (e.g., other brain disorders, alcohol/sedative withdrawal).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pruritus Severity. Timepoint: Before the intervention and after 1 week, 2 weeks and 4 weeks after the intervention. Method of measurement: Using the Visual Analogue Scale.;Impact of Pruritus on Quality of Life. Timepoint: Before the intervention and after 1 week, 2 weeks and 4 weeks after the intervention. Method of measurement: Using the 5-D Itch Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmirAhmad Shojaei
Bandare-abbas University of Medical Sciences
Outcome results
None listed