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Investigation of the simultaneous effect of lidocaine and bupivacaine compared to bupivacaine alone on the supraclavicular block

Investigation of the simultaneous effect of lidocaine and bupivacaine compared to bupivacaine alone on the supraclavicular block in patients requiring upper limb surgery, a parallel randomized controlled trial.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250506065621N1
Enrollment
70
Registered
2025-05-24
Start date
2025-06-22
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

All Conditions Requiring Upper Extremity Surgery. Pain, not elsewhere classified

Interventions

Intervention 1: Intervention group: In this group, all patients will be given local and regional anesthesia. To induce anesthesia, 1 to 2 mg of midazolam, 50 to 100 micrograms of fentanyl are injected

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: BMI more than 20 and less than 35 American Society of Anesthesiologists Class of I, II and III Candidate for Elective Upper Extremity Surgery Full informed consent until the end of the treatment and examination stages

Exclusion criteria

Exclusion criteria: History of Allergic Reaction to Anesthesia Diseases accompanied by Hypotension Neurological Diseases Psychiatric Diseases Use of Anticoagulants Accompanied Infections Cardiac Conductive Diseases, especially Blocks Active Liver Diseases Gastrointestinal Diseases Pulmonary Diseases such as Respiratory Distress Syndrome, Asthma, Active Infections or COPD Drug Abuse Alcohol Use

Design outcomes

Primary

MeasureTime frame
Time to onset of sensory block. Timepoint: 5, 10, 15, 30 minutes after injection. Method of measurement: Pinprick Test.;Time to onset of motor block. Timepoint: 5, 10, 15, 30 minutes after injection. Method of measurement: Lovett Rating Scale Test.;Duration of sensory block. Timepoint: Every 10 minutes until the effect of the medicine wears off. Method of measurement: Pinprick Test.;Duration of motor block. Timepoint: Every 10 minutes until the effect of the medicine wears off. Method of measurement: Lovett Rating Scale Test.

Secondary

MeasureTime frame
Pain. Timepoint: 1, 6 and 12 hours after intervention. Method of measurement: Numerical Rating Scale for Pain.;The time from the end of the desired anesthetic injection to the request for the first narcotic. Timepoint: 24 hours. Method of measurement: Minutes to receive narcotics based on patient record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Atef Yekta

Tehran University of Medical Sciences

atefyekta@tums.ac.ir+98 21 8490 1000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026