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The effect of probiotic supplementation on the incidence of seizures in epilepsy patients

The effctt of probiotic supplementation on the occurrence of seizures in epileptic patients with irritable bowel syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250503065581N1
Enrollment
54
Registered
2025-05-29
Start date
2025-05-22
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable bowel syndrome. Irritable bowel syndrome

Interventions

Intervention 1: Intervention group: Patients diagnosed with epilepsy have irritable bowel syndrome. Intervention 2: Control group: Patients diagnosed with epilepsy have irritable bowel syndrome.

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to 64 Years

Inclusion criteria

Inclusion criteria: Patients with IBS Patients with idiopathic epilepsy History of seizures at least twice a month for at least the past year Age 17 to 64 years Absence of secondary causes of seizures such as encephalitis, stroke, and brain tumor

Exclusion criteria

Exclusion criteria: Antibiotic use within the past 3 months Recent gastrointestinal infections within the past 3 months Change in anticonvulsant medication therapy for patients during the study period Receipt of non-drug seizure treatments

Design outcomes

Primary

MeasureTime frame
Seizure frequency. Timepoint: 3 months after the start of the study. Method of measurement: Number.;Type of Seizure. Timepoint: 3 months after the start of the study. Method of measurement: Brain scan.;Number and duration of epileptiform discharges. Timepoint: 3 months after the start of the study. Method of measurement: Brain scan.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSanaz Chegini

Ardabil University of Medical Sciences

sanaz.chegini1369@gmail.com+98 41 3660 4790

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026