Dependence on enabling machines and devices, not elsewhere classified. Dependence on respirator
Conditions
Interventions
Intervention 1: Intervention group: Intervention group: In this study, a machine learning model was first developed (data cleaning and preparation, data division into training and testing, machine lea
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Intubated patients in the ICU for at least 12 hours who are ready for weaning from the ventilator undergoing a spontaneous breathing trial (SBT) with an oxygenation level (FiO2) of less than 50% positive end-expiratory pressure (PEEP) = 5 cmH2O pressure support (PS) = 5 cmH2O for 30 minutes to hours appropriate Glasgow Coma Scale (GCS) score (= 8–10) PaO2/FiO2 ratio > 150 ability to cough effectively and clear secretions adequate respiratory muscle tone stable hemodynamics and age range of 18–75 years
Exclusion criteria
Exclusion criteria: Patients with severe neurological disorders those unable to breathe due to neuromuscular diseases patients with a do-not-resuscitate (DNR) status Patients with airway obstruction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extubation Failure Rates. Timepoint: Within 48 hours after Extubation. Method of measurement: Documentation of the need for re-intubation in the patient's medical record within 48 hours after extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of ICU stay. Timepoint: From ICU admission to ICU discharge. Method of measurement: Calculation of the number of ICU hospitalization days from admission to discharge.;ICU mortality. Timepoint: up to the time of ICU discharge. Method of measurement: Documentation of the patient’s final status (alive or deceased) in the medical record.;Occurrence of post-extubation pulmonary edema. Timepoint: within 48 to 72 hours after extubation. Method of measurement: Clinical diagnosis and chest imaging.;Occurrence of aspiration after extubation. Timepoint: within 48 to 72 hours after extubation. Method of measurement: Clinical diagnosis or imaging evidence and documented.;Clinical assessment of respiratory muscle strength and inability to maintain effective ventilationOccurrence within 48 hours of extubationPost-extubation muscle fatigue. Timepoint: within 48 hours of extubation. Method of measurement: Clinical assessment of respiratory muscle strength and inability to maintain effective ventilationOccurrence.;Comparison of prediction accuracy of AI model and ICU physicians. Timepoint: After extubation and observing the final outcome (success or failure). Method of measurement: Comparison of sensitivity, specificity, positive and negative predictive value of AI model with physicians' decision in predicting extubation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohadeseh Rajabi
Mashhad University of Medical Sciences
Outcome results
None listed