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Investigating the Effect of Manual Therapy (Physiotherapy) on Migraine Headache

Investigating the Effect of Upper Cervical Manual Therapy on Heart Rate Variability Parameters in Patients with Episodic Migraine

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250502065564N1
Enrollment
40
Registered
2025-05-08
Start date
2025-05-10
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Episodic migraine. Migraine

Interventions

Intervention 1: Intervention Group 1: Upper cervical manual therapy using the mobilization technique, applied over 4 treatment sessions on alternate days. Mobilization, one of the manual therapy techn

Sponsors

Tarbiat Modares University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Diagnosis of episodic migraine by a neurologist (at least 4 headache days per month) according to the international Headache Society (IHS) criteria Women aged between 18 and 50 years

Exclusion criteria

Exclusion criteria: Having conditions such as diabetes mellitus, other neurological disorders, systemic diseases such as fibromyalgia and rheumatoid arthritis, malignancy, osteoporosis, cervical radiculopathy and discopathy, or vertebral fracture Received nerve blocks and physiotherapy treatments in the past 6 months Severe physical and psychiatric limitations Having other primary and secondary headaches, such as medication overuse headaches Cervical spine instability and positive pre-manipulative tests Any cardiovascular disease such as arrhythmia, coronary artery disease, and hypertension

Design outcomes

Primary

MeasureTime frame
Nonlinear heart rate variability parameters. Timepoint: Before the start of the intervention and 48 hours after the final intervention session. Method of measurement: Electrocardiograph device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Ahmadiazar

School of Medical Sciences, Tarbiat Modares University (TMU)

mohsen.ahmadi@modares.ac.ir+98 21 8895 3071

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026