Effectiveness of CBT on Schizophrenia Symptoms in Adolescents

Evaluating Cognitive Behavioral Therapy in Adolescent Schizophrenia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250502065561N1

Enrollment

Registered

2025-12-12

Start date

2025-06-04

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia. Schizophrenia

Interventions

Intervention 1: Participants will receive structured Cognitive Behavioral Therapy based on a predefined protocol (adapted from the 12-session framework of Kingdon and Price, 2009). The intervention fo

Eligibility

Sex/Gender

All

Age

14 Years to 17 Years

Inclusion criteria

Inclusion criteria: Diagnosis of schizophrenia Normal intelligence Ninth grade literacy Age between fourteen and seventeen years

Exclusion criteria

Exclusion criteria: Receiving cognitive behavioral therapy prior to the study Concurrent personality disorder diagnosis Diagnosis of schizoaffective disorder or bipolar disorder History of organic psychosis

Design outcomes

Primary

Measure	Time frame
The primary outcome is the positive symptom score measured by the Positive and Negative Syndrome Scale. Timepoint: Baseline assessments will be conducted four times for the first participant, five times for the second participant, and six times for the third participant. Intervention-phase assessments will be performed at sessions three, six, nine, and twelve, immediately after the completion of each respective session. To evaluate the maintenance of treatment effects, two follow-up assessments will be conducted at one month and three months. Method of measurement: The Positive and Negative Syndrome Scale is used to measure the positive symptom score.;The primary outcome is the negative symptoms score, measured using the Positive and Negative Syndrome Scale (PANSS). Timepoint: Baseline assessments will be conducted four times for the first participant, five times for the second participant, and six times for the third participant. Intervention-phase assessments will be performed at sessions three, six, nine, and twelve, immediately after the completion of each respective session. To evaluate the maintenance of treatment effects, two follow-up assessments will be conducted at one month and three months. Method of measurement: The Positive and Negative Syndrome Scale is used to measure the negative symptom score.;The primary outcome is the general psychopathology score measured by the Positive and Negative Syndrome Scale. Timepoint: Baseline assessments will be conducted four times for the first participant, five times for the second participant, and six times for the third participant. Intervention-phase assessments will be performed at sessions three, six, nine, and twelve, immediately after the completion of each respective session. To evaluate the maintenance of treatment effects, two follow-up assessments will be conducted at one month and three months. Method of measurement: The Positive and Negative Syndrome Scale is used to measure the general psychopathology	—

Measure

Time frame

The primary outcome is the positive symptom score measured by the Positive and Negative Syndrome Scale. Timepoint: Baseline assessments will be conducted four times for the first participant, five times for the second participant, and six times for the third participant. Intervention-phase assessments will be performed at sessions three, six, nine, and twelve, immediately after the completion of each respective session. To evaluate the maintenance of treatment effects, two follow-up assessments will be conducted at one month and three months. Method of measurement: The Positive and Negative Syndrome Scale is used to measure the positive symptom score.;The primary outcome is the negative symptoms score, measured using the Positive and Negative Syndrome Scale (PANSS). Timepoint: Baseline assessments will be conducted four times for the first participant, five times for the second participant, and six times for the third participant. Intervention-phase assessments will be performed at sessions three, six, nine, and twelve, immediately after the completion of each respective session. To evaluate the maintenance of treatment effects, two follow-up assessments will be conducted at one month and three months. Method of measurement: The Positive and Negative Syndrome Scale is used to measure the negative symptom score.;The primary outcome is the general psychopathology score measured by the Positive and Negative Syndrome Scale. Timepoint: Baseline assessments will be conducted four times for the first participant, five times for the second participant, and six times for the third participant. Intervention-phase assessments will be performed at sessions three, six, nine, and twelve, immediately after the completion of each respective session. To evaluate the maintenance of treatment effects, two follow-up assessments will be conducted at one month and three months. Method of measurement: The Positive and Negative Syndrome Scale is used to measure the general psychopathology

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamideh Zamani Gharachamani

Islamic Azad University

hamidehzamani666@gmail.com+98 914 116 4870

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026