Liver cirrhosis. Fibrosis and cirrhosis of liver
Conditions
Interventions
Intervention 1: Intervention group: These patients will be randomly supplemented with monthly single intramuscular dose of 200,000 IU cholecalciferol /vitamin D3 for 6 months (Vitamin D Group). Interv
Sponsors
King Edward Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients having age between 30-60 years both male and female having liver cirrhosis receiving vitamin D supplementation (as per operational definition) along with standard therapy of treatment
Exclusion criteria
Exclusion criteria: Patients having metastatic tumor of liver. Patients who are unable to understand local languages. Non cooperative patients Critical cases (ICU admitted, mechanical ventilation, coma patient, GCS score less than 10) any patients with prior vitamin D treatment in the previous two months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in quality of life and patient-reported outcomes, assessed using the Chronic Liver Disease Questionnaire (CLDQ). Timepoint: After 6 months of treatment. Method of measurement: This outcome will be measured by comparing the CLDQ scores (categorized as high or low) between the Vitamin D group and the placebo group. | — |
Countries
Pakistan
Contacts
Public ContactDr. Muhammad Umer Sheikh
King Edward Medical University
Outcome results
None listed