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Clinical trial of topical anti-eczema formulation from Capparis spinosa

Clinical study investigating the anti-eczema effect of the plant Capparis spinosa.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250420065401N1
Enrollment
72
Registered
2025-08-14
Start date
2025-07-23
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

eczema. Atopic dermatitis

Interventions

Intervention 1: Intervention group: Receiving a topical peel-off gel containing Cappais Spinosa root extract in natural vinegar. Other ingredients: PVA, PEG, TWEEN 20. To be used twice daily for two w

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The eczema diagnosis has been confirmed by a dermatologist in all individuals All ages and both genders with mild to moderate eczema severity, as assessed by the Eczema Area and Severity Index (EASI) Patients must not have used topical or systemic treatments for at least three months prior to the start of the study Willingness to cooperate in the study and complete the informed consent form

Exclusion criteria

Exclusion criteria: Patients with weeping lesions Patients with lesions that have been burned or traumatized Hypersensitivity to the ingredients of the medication Patients who have another active skin disease in addition to eczema Kidney and liver dysfunction Involvement with uncontrolled chronic diseases Pregnancy and breastfeeding Individuals who have participated in other clinical trials in the past 1 month

Design outcomes

Primary

MeasureTime frame
Severity of eczema. Timepoint: Before the intervention and 2 weeks after the end of the intervention. Method of measurement: Eczema Area and Severity Index (EASI).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Salehi

Shiraz University of Medical Sciences

mry_salehi@sums.ac.ir+98 71 3242 4128

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026