organic toothpaste

Investigating the effect of toothpaste formulation containing pilocarpine loaded in nano mesoporous silica on the salivasecretion rate in people with dry mouth compared to pilocarpine.

Status

Active, not recruiting

Phases

Phase 3

Study type

Observational

Source

IRCT

Registry ID

IRCT20250420065395N1

Enrollment

Registered

2025-12-13

Start date

2026-04-21

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry mouth. Disturbances of salivary secretion

Interventions

Intervention 1: Control group: In this group, people will take the non-medicated toothpaste without knowing they are in the placebo group. They will be examined for saliva samples and questionnaires e

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: the incidence of mouth dryness is 2 months or more The patient is 20 years old or older.

Exclusion criteria

Exclusion criteria: the criteria for inattention to the study were :to asthma Narrow-angle glaucoma acute iritis allergy to the ingredients of toothpaste pregnancy breastfeeding people who were able to treat their mouths using artificial saliva People who treat their dry mouth using pilocarpine.

Design outcomes

Primary

Measure	Time frame
Saliva volume. Timepoint: Once every 7 days for 2 to 3 months. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Nesa Mousavipour

Ahvaz University of Medical Sciences

nesa72.moosavi@gmail.com0989167239970

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026