Muscle mass reduction due to aging. Other specified disorders of muscle
Conditions
Interventions
Intervention 1: First intervention group: This group performed functional training combined with blood flow restriction (BFR) for a total of 24 sessions (3 days per week for 8 weeks). The BFR pressure
Sponsors
Alzahra University
Eligibility
Sex/Gender
Female
Age
60 Years to 70 Years
Inclusion criteria
Inclusion criteria: Elderly individuals (over 60 years of age) No muscular and/or joint limitations in the involved areas No history of fractures in the past 6 months Having medical clearance to participate No history of cardiovascular diseases No hypertension No diabetes No neuromuscular disorders No metabolic diseases Healthy, community-dwelling women No supplement consumption Completion of a health questionnaire No injuries or illnesses during the intervention No use of hormonal medications No use of medications (e.g., for blood pressure or blood sugar control) No specific dietary regimens Ability to attend training sessions No participation in regular exercise programs Completion of the informed consent form
Exclusion criteria
Exclusion criteria: Inability to perform initial assessments Having a muscle mass index (MMI) greater than 45.45 kg/m² Cardiovascular diseases Hypertension Diabetes Supplement consumption Use of hormonal medications Use of medications (e.g., for blood pressure or blood sugar control) Specific dietary regimens History of fractures in the past 6 months Metabolic diseases Neuromuscular disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myostatin. Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: ELISA measurement kits.;Follistatin. Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: ELISA measurement kits.;Growth hormone. Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: ELISA measurement kits.;Homocysteine. Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: ELISA measurement kits.;Follistatin to Myostatin Ratio. Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: To measure the Follistatin to Myostatin ratio, a blood sample is taken, then the plasma or serum concentrations of both proteins are measured using the ELISA method, and the first value is divided by the second. | — |
Secondary
| Measure | Time frame |
|---|---|
| Upper body strength. Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: Handgrip test.;Lower body strength. Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: Squat test.;Quality of life. Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: LIPAD Questionnaire.;Timed Up and Go (TUG). Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: Using the Timed Up and Go (TUG) test.;30 Seconds Sit To Stand Test. Timepoint: One day before the first session and 48 hours after the last training session. Method of measurement: 30-Second Chair Stand Test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElham Shakoor
Alzahra University
Outcome results
None listed