"Studying the effect of combining two drug groups in patients who are candidates for bronchoscopy"

Comparison of the sedative effect of the combination of dexmedetomidine and ketamine with propofol and fentanyl in patients who are candidates for bronchoscopy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250418065371N1

Enrollment

Registered

2025-04-28

Start date

2025-06-05

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with respiratory problems and requiring diagnostic bronchoscopy. Respiratory disorder, unspecified

Interventions

Intervention 1: In the intervention group, after obtaining consent, eligible individuals were randomly selected. In the intervention group, dexmedetomidine was injected from Exir Iran Company at a dos

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients Indication for diagnostic bronchoscopy ASA 1 and 2 patients

Exclusion criteria

Exclusion criteria: History of psychiatric problems and psychological drug treatment ASA 3 and above History of allergies to medications used Substance abuse Patient dissatisfaction Pregnancy Chronic use of painkillers Emergency cases and unstable patients

Design outcomes

Primary

Measure	Time frame
The patient's hemodynamic fluctuations during the procedure include a decrease or increase in systolic blood pressure, bradycardia or tachycardia, and the patient's intolerance to bronchoscopy. These items are also recorded every 5 minutes during recovery, along with other complications such as nausea, vomiting, etc. Timepoint: During the procedure, the patient's hemodynamic fluctuations during the procedure, including a drop or increase in systolic blood pressure, bradycardia or tachycardia, the patient's intolerance to bronchoscopy, and these items are recorded every 5 minutes during recovery, along with other new complications such as nausea and vomiting, etc. The evaluation of these items, as mentioned above, and every 5 minutes during recovery, along with other complications such as nausea and vomiting, the length of recovery time, and the patient's pain during recovery, as well as the bronchoscopist's satisfaction, are recorded based on a score of excellent (very easy to perform) - satisfactory (difficult to perform) - unsatisfactory (unable to perform). Method of measurement: Assessing the patient's hemodynamics and pain during the procedure based on the Ramsy criteria and assessing hemodynamics and pain based on the NSR criteria during recovery.	—

Measure

Time frame

The patient's hemodynamic fluctuations during the procedure include a decrease or increase in systolic blood pressure, bradycardia or tachycardia, and the patient's intolerance to bronchoscopy. These items are also recorded every 5 minutes during recovery, along with other complications such as nausea, vomiting, etc. Timepoint: During the procedure, the patient's hemodynamic fluctuations during the procedure, including a drop or increase in systolic blood pressure, bradycardia or tachycardia, the patient's intolerance to bronchoscopy, and these items are recorded every 5 minutes during recovery, along with other new complications such as nausea and vomiting, etc. The evaluation of these items, as mentioned above, and every 5 minutes during recovery, along with other complications such as nausea and vomiting, the length of recovery time, and the patient's pain during recovery, as well as the bronchoscopist's satisfaction, are recorded based on a score of excellent (very easy to perform) - satisfactory (difficult to perform) - unsatisfactory (unable to perform). Method of measurement: Assessing the patient's hemodynamics and pain during the procedure based on the Ramsy criteria and assessing hemodynamics and pain based on the NSR criteria during recovery.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Eshraghi

Ghoum University of Medical Sciences

Eshraghi31@gmail.com0098212920875

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026