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Effect of dual training on cathepsin B and mayostatin

The effect of dual-task (Cognitive-Functional) training on the biomarkers Cathepsin B and Myostatin in elderly individuals

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250415065336N1
Enrollment
20
Registered
2025-10-08
Start date
2025-07-11
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elderly.

Interventions

Intervention 1: Intervention group: Participants: 12 individuals (male/female) /"Participants will complete an 8-week dual-task (functional-cognitive) training program consisting of:• Frequency: 2 ses

Sponsors

Kharazmi University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age 60–80 years No participation in exercise training or physiotherapy during the intervention No use of specific sports or medicinal supplements No history of acute chronic cardiovascular or metabolic diseases No open surgery in the past 6 months to 1 year

Exclusion criteria

Exclusion criteria: Participant's unwillingness or lack of interest to continue in the study Physician's recommendation for withdrawal from the study Non-participation in 3 consecutive training sessions Non-participation in the post-test

Design outcomes

Primary

MeasureTime frame
Serum Cathepsin B level. Timepoint: Pre and Post- Test (48 hours before and after 8 weeks of dual training). Method of measurement: Abcam Human Cathepsin B ELISA Kit.;Myostatin level. Timepoint: Pre and Post-test. Method of measurement: ELYZA kit.

Secondary

MeasureTime frame
Cognitive performance. Timepoint: Pre and Post-test (72 hours before and after 8 weeks of dual training). Method of measurement: Stroop test.;Functional-cognitive test. Timepoint: Pre and Post-test (72 hours before and after 8 weeks of dual training. Method of measurement: Timed Up and Go test.;Aerobic fitness. Timepoint: Pre and Post-test (72 hours before and after 8 weeks of dual training. Method of measurement: 6-minute walk test.;Fat profile. Timepoint: Pre and Post-test (48 hours before and after 8 weeks of dual training. Method of measurement: Elyza kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Sadat Zendepour

Kharazmi University

fatemehzendehpour@gmail.com+98 21 2222 8001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026