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The effect of intense oocyte granulation on the success of infertility treatment with ICSI.

Studying the effect of severe oocyte granulation on the outcomes of assisted reproductive treatment using intracytoplasmic sperm injection (ICSI)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250414065322N1
Enrollment
140
Registered
2025-07-27
Start date
2025-07-22
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertilization rate and number of embryos. Complications associated with artificial fertilization

Interventions

Intervention 1: Intervention group: Oocytes with severe granulation that underwent ICSI process like the control group. Intervention 2: Control group: All procedures including ovulation induction, den

Sponsors

Bandare-abbas University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Infertile Underwent assisted reproductive treatment using the ICSI/FET method at this center Ovulation induction performed using the antagonist protocol Gonadotropin dose and type recorded in the patient’s medical file Availability of complete information on oocyte quality and granulation assessment in the records Availability of information related to the embryo freezing, thawing, and transfer process in the patient's file

Exclusion criteria

Exclusion criteria: Severe underlying diseases that make the intervention dangerous Complete lack of file information or lack of access to necessary data Refusal or withdrawal from participation in the study

Design outcomes

Primary

MeasureTime frame
Number of Embryos. Timepoint: From the start of the intervention to the formation of fertilization. Method of measurement: 24 hours after ICSI, zygote formation is monitored by observing the formation of two pronuclei (2PN) in the cytoplasm. Three days later, the number of resulting embryos and their quality are assessed.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRezvan Moradi

Bandare-abbas University of Medical Sciences

r.mo8080@hums.ac.ir+98 44 3672 0698

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026