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Clinical comparison of three resin-based materials in fissure sealants for permanent first molars in children aged 6 to 12 years

Clinical comparison of three resin-based materials in fissure sealants for permanent first molars in children aged 6 to 12 years: A randomized clinical trial with 6-month follow-up

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250414065317N1
Enrollment
20
Registered
2025-07-29
Start date
2025-07-23
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The occlusal surface of the permanent first molar with a score of 0 to 2 according to the International Caries Diagnosis and Assessment System (ICDAS 0, 1 & 2). Caries limited to enamel

Interventions

Intervention 1: Intervention group: Flowable composite Z350. Intervention 2: Intervention group: Clinpro Sealant. Intervention 3: Intervention group: Cobalt Sealant.

Sponsors

Bojnourd University of Medical Sciences
Lead Sponsor
Bojnourd University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: The child should be cooperative (score 3 or 4 on the Frankl scale). Have at least one permanent first molar fully erupted. Their occlusal surface should have a score of 0 to 2 according to the International Caries Diagnosis and Assessment System (ICDAS 0, 1 & 2). It should be possible to isolated the tooth with rubber dam.

Exclusion criteria

Exclusion criteria: Children who are uncooperative (score 1 or 2 on the Frankl scale). Their occlusal surface should have a score of 3 to 6 according to the International Caries Diagnosis and Assessment System (ICDAS 3-6). Children who have any history of systemic problems or allergies, parafunctional activity, use of any drug affecting saliva flow or developmental disorders in teeth.

Design outcomes

Primary

MeasureTime frame
Prevention of decay. Timepoint: At the beginning of the study and 1, 3 and 6 months later. Method of measurement: By a pediatric dentist according to the Simonsen criteria.;Retention. Timepoint: At the beginning of the study and 1, 3 and 6 months later. Method of measurement: By a pediatric dentist according to the Simonsen criteria.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzieh Sahebnasagh

Bojnourd University of Medical Sciences

marzieh.saheb@gmail.com+98 58 3272 8568

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026