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Effectiveness of antibiotic administration every other day and every day in prophylaxis of children with reflux disease

Comparative of the effectiveness of Antibiotic administration as a sequence every two days and daily in the medical prophylaxis of children with vesicoureteral reflux

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250412065295N1
Enrollment
40
Registered
2025-05-29
Start date
2025-05-13
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary reflux. Urethritis and urethral syndrome

Interventions

Intervention 1: Intervention group: In this group, cephalexin at a dose of 15mg/kg from Kowsar Pharmaceutical Company (according to Nelson) is administered once a day every night at a specific time (f

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Months to 15 Years

Inclusion criteria

Inclusion criteria: Children with primary vesicoureteral reflux grade 4 and 5 Infants under one year of age with primary vesicoureteral reflux of any degree Children with primary vesicoureteral reflux of any degree accompanied by recurrent urinary tract infections

Exclusion criteria

Exclusion criteria: Children with secondary vesicoureteral reflux Children with grades 1, 2, and 3 vesicoureteral reflux without recurrent urinary tract infections or bowel and bladder dysfunction

Design outcomes

Primary

MeasureTime frame
Urinary reflax. Timepoint: every month untill1 year. Method of measurement: Urine culture.

Secondary

MeasureTime frame
Frequent urination. Timepoint: Every month to a year. Method of measurement: Yes - No.;Fever. Timepoint: Every month to a year. Method of measurement: Yes - No.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Zamen Salehi Fard

Shahre-kord University of Medical Sciences

salehifard.ali@skums.ac.ir+98 38 3334 9509

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026