Evaluation effect of sevelamer carbonate on mortality of oral aluminum phosphide toxicity

Evaluation effect of paraffin oil based sevelamer carbonate solution on mortality of oral aluminum phosphide toxicity

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250412065294N1

Enrollment

Registered

2025-07-09

Start date

2025-05-22

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aluminum phosphide toxicity. Finding of unspecified substance, not normally found in blood

Interventions

Intervention 1: Intervention group: 1600 mg sevelamer with 100 cc parafin during the first 2 hours. Intervention 2: Intervention group: 100 cc parafin during the first 2 hours.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: patients over 18 years old positive Silver nitrate tes due to oral aluminum phosphide toxicity

Exclusion criteria

Exclusion criteria: sensivity to paraffin

Design outcomes

Primary

Measure	Time frame
Mortality rate. Timepoint: until hospital stay. Method of measurement: Daily patient visit.	—

Secondary

Measure	Time frame
Determining the duration of hospitalization due to oral aluminum phosphide poisoning in the intervention group (the group receiving Sevellamer tablets at a dose of 1600 mg during the first 2 hours along with other required drug therapies). Timepoint: time of patients hospitalization. Method of measurement: Daily patient visit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoja Qobadighadikolaei

Mazandaran University of Medical Sciences

roja.ghobadi@ail.com+98 11 4221 8011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026