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Studying the effect of montelukast in reducing pain after surgery

Investigation of Preoperative Oral Montelukast Prescription on Postoperative Pain Levels Following Zygomaticomaxillary Complex Fracture Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250412065292N1
Enrollment
80
Registered
2025-06-08
Start date
2025-08-23
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Zygomaticomaxillary complex fracture. Fracture of malar, maxillary and zygoma bones, unspecified

Interventions

Intervention 1: Intervention group: At time intervals of 0, 6, 12, and 24 hours before transfer to the operating room, patients will receive a 40 mL glass of fruit juice containing 10 mg of monteluka

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The participating patients who have zygomaticomaxillary complex fracture Patients aged between 18 and 60 years Patients of both sexes, male and female Patients with a BMI of less than 30 kg/m² (non-obese)

Exclusion criteria

Exclusion criteria: Preoperative use or dependence on narcotic drugs Having peptic ulcer disease, hepatic or renal dysfunction, or psychiatric disorders Allergy to amide local anesthetics and narcotics, and a history of seizures Cases where the participant requires intensive care unit admission after surgery

Design outcomes

Primary

MeasureTime frame
Postoperative pain intensity score measured using the Visual Analogue Scale from 0 to 10, in patients undergoing surgery for zygomaticomaxillary complex fractures, comparing Montelukast and control groups. Timepoint: Pain intensity will be assessed immediately after recovery and every two hours for a total duration of 12 hours. Method of measurement: The outcome was measured using the Visual Analogue Scale for pain intensity.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarokh Farhadi Shabestari

Tabriz University of Medical Sciences

drfarrokhfarhadi@gmail.com+98 41 3335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026