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The premedication effect of Diclofenac in pain control after mandibular wisdom tooth surgery

Evaluation of the premedication effect of Diclofenac compared to Ibuprofen in pain control after mandibular third molar surgery: a randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250410065280N1
Enrollment
75
Registered
2025-05-14
Start date
2025-05-22
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mandibular third molar surgery.

Interventions

Intervention 1: Intervention group 1: Receive a single dose of 100 mg of Alborz Darou diclofenac tablets one hour before surgery. Intervention 2: Intervention group 2: Intervention group: Received a s

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Written consent to participate in the research project Indications for surgery of impacted wisdom teeth with mesiangular, horizontal and vertical orientation according to Winter classification and class I, II and position A, B according to Pell and Gregory classification Alertness Cooperation, and ability to use medication Age 18 to 35 years

Exclusion criteria

Exclusion criteria: Indication for surgery: impacted mandibular wisdom teeth with a distoangular and transverse orientation and Class III (there is no space between the distal surface of the second molar and the mandibular ramus) and position C (the occlusal surface of the third molar is below the cervical line of the second molar). Contraindications to NSAID use (allergy to NSAIDs, patients with coronary artery bypass surgery, pregnancy, presence of active peptic ulcer, and renal failure) Using other analgesic medications Drug use and addiction

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: 1,3,6,12,24 hours after surgery. Method of measurement: Visual analog scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeed Moslehpour

Birjand University of Medical Sciences

sa.moslehpour98@gmail.com+98 56 3238 1706

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026