Evaluation of electrospun wound dressing on burn wound

Evaluation of electrospun nanofibrous wound dressing on superficial second-degree burn wounds (clinical trial phase I)

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250408065259N1

Enrollment

Registered

2025-12-21

Start date

2024-08-12

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial second-degree burn wounds. Burn of second degree, body region unspecified

Interventions

Intervention 1: This intervention includes patients with superficial second-degree burn wounds who receive a polycaprolactone/gelatin electrospun nanofibrous dressing with an area of ??100 cm2 (10 cm

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18–70 years Both sexes Superficial second-degree burn wounds No prior burns at the current site No acute psychiatric disorders No comorbidities No immunosuppressive therapy No massive unstable trauma Completion of informed consent form

Exclusion criteria

Exclusion criteria: First and third degree burn wounds burns on joints, face, perineum Pregnancy or breastfeeding Patients with diabetic and infected wounds Presence of a chronic skin disease

Design outcomes

Primary

Measure	Time frame
Re-epithelialization. Timepoint: Day 0, 4, 9, and 14. Method of measurement: Photography using Image J software.;Wound healing quality. Timepoint: Day 0, 4, 9, and 14. Method of measurement: Surgeon evaluation through scoring poor, moderate, good, and excellent.;Wound dressing change. Timepoint: During the treatment period. Method of measurement: Surgeon's evaluation.;Patient comfort level. Timepoint: End of study. Method of measurement: By the patient through scoring of dissatisfaction, moderate, good and excellent.;Pain. Timepoint: Day 0, 4, 9, and 14. Method of measurement: Visual Analogue Scale.;Wound dressing adhesion. Timepoint: End of study. Method of measurement: Surgeon's evaluation through scoring of dissatisfaction, moderate, good and excellent.;Erythema. Timepoint: End of study. Method of measurement: Surgeon's evaluation through scoring of Very low, low, moderate and severe.;Edema. Timepoint: End of study. Method of measurement: Surgeon's evaluation through scoring of without edema, low, moderate and severe.	—

Measure

Time frame

Re-epithelialization. Timepoint: Day 0, 4, 9, and 14. Method of measurement: Photography using Image J software.;Wound healing quality. Timepoint: Day 0, 4, 9, and 14. Method of measurement: Surgeon evaluation through scoring poor, moderate, good, and excellent.;Wound dressing change. Timepoint: During the treatment period. Method of measurement: Surgeon's evaluation.;Patient comfort level. Timepoint: End of study. Method of measurement: By the patient through scoring of dissatisfaction, moderate, good and excellent.;Pain. Timepoint: Day 0, 4, 9, and 14. Method of measurement: Visual Analogue Scale.;Wound dressing adhesion. Timepoint: End of study. Method of measurement: Surgeon's evaluation through scoring of dissatisfaction, moderate, good and excellent.;Erythema. Timepoint: End of study. Method of measurement: Surgeon's evaluation through scoring of Very low, low, moderate and severe.;Edema. Timepoint: End of study. Method of measurement: Surgeon's evaluation through scoring of without edema, low, moderate and severe.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamad Pezeshki Modaress

Iran University of Medical Sciences

pezeshkimodaress.m@iums.ac.ir+98 21 8871 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026