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Efficacy of hydrodissection of Median nerve on pain and function of participants with carpal tunnel syndrome

Efficacy of hydrodissection of Median nerve on pain and function of patients with carpal tunnel syndrome

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250406065229N1
Enrollment
40
Registered
2025-07-08
Start date
2025-07-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal tunnel syndrome. Carpal tunnel syndrome

Interventions

Intervention 1: Intervention group: One injection with 1 cc of methylprednisolone, 1 cc of 2% lidocaine, and 1.5 cc of normal saline (total 3.5 cc) using the hydrodissection technique. Intervention 2:

Sponsors

Artesh University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Diagnosis of mild to moderate carpal tunnel syndrome by electrodiagnostic and sonographic examinations Symptoms of carpal tunnel syndrome lasting more than three months Resistance to drug treatment and splinting

Exclusion criteria

Exclusion criteria: No history of polyneuropathy, brachial plexopathy, thoracic outlet syndrome, or wrist surgery. No history of inflammatory arthritis, hypothyroidism, pregnancy, rheumatologic disorders, or pacemaker. No current use of warfarin, previous steroid injection for CTS, trauma or neoplasm at the injection site. Allergy to corticosteroids or skin infection (injection site)

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: At the beginning of the study (before the intervention), one month and three months after the injection. Method of measurement: Visual Analog Scale.;Symptoms. Timepoint: At the beginning of the study (before the intervention), one month and three months after the injection. Method of measurement: Boston Questionnaire.;Electrodiagnostic criteria. Timepoint: At the beginning of the study (before the intervention), one month and three months after the injection. Method of measurement: Natus electromyography device.;Ultrasound examinations. Timepoint: At the beginning of the study (before the intervention), one month and three months after the injection. Method of measurement: Sonoscape ultrasound device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Sheikh Alishahi

Artesh University of Medical Sciences

dr.zahraalishahi@gmail.com+98 912 443 3886

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026