The topics and diseases studied in this research include type 2 diabetes and related anthropometric indices such as height, weight, body composition, and blood pressure. Additionally, the effects of resistance, endurance, and combined exercise training on biochemical markers including nitric oxide (NO), eNOS, iNOS, Apo A-I, and lipid profile in women with type 2 diabetes are examined. This study is designed to evaluate the impact of exercise interventions on the management and improvement of hea
Conditions
Interventions
Intervention 1: Resistance Training Group:Participants in this group, after one week of adaptation training, will perform resistance training three times per week for eight weeks. Each session include
Sponsors
University of Mohaghegh Ardabili
Eligibility
Sex/Gender
Female
Age
48 Years to 58 Years
Inclusion criteria
Inclusion criteria: No history of cardiovascular diseases No physical activity in the past six months No high blood pressure Non-smoker Use of the same type of medication for T2DM by all participants No presence of wounds on the body No musculoskeletal disorders that prevent physical activity
Exclusion criteria
Exclusion criteria: In case of irregular attendance Injury or physical problems preventing activity In case of withdrawal Changes in medications affecting the results Onset of a new illness Excessive absence beyond the allowed limit
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anthropometric indices include height, weight, body composition, body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), waist-to-hip ratio (WHR), and novel indices such as the Body Roundness Index (BRI) and Visceral Adiposity Index (VAI). These indices play a significant role in predicting and diagnosing type 2 diabetes, and changes in these measures can indicate improvement or worsening of patients’ conditions. Timepoint: The measurement points for anthropometric indices will include two stages: pre-test (before the start of the intervention) and post-test (48 hours after the completion of the 8-week training program). Method of measurement: Anthropometric indices, including height, weight, waist and hip circumference, will be measured using a standard stadiometer and measuring tape, while body composition will be assessed with a body analyzer device. Subsequently, indices such as BMI, WHR, WHtR, BRI, and VAI will be calculated using the measured data and the relevant formulas.;Biochemical indices include nitric oxide (NO) and related enzymes such as eNOS and iNOS, which play important roles in regulating vascular function and glucose metabolism. Changes in these indices can indicate the body’s response to exercise interventions. Timepoint: The time points for measuring biochemical indices, including nitric oxide (NO), eNOS, and iNOS, in this study will consist of two stages: pre-test (before the start of the intervention) and post-test (48 hours after the completion of the 8-week training program). Method of measurement: Blood sampling for the measurement of biochemical indices (nitric oxide, eNOS, and iNOS) will be conducted at two time points: pre-test (before the start of the intervention) and post-test (48 hours after the completion of the 8-week training program). Fasting blood samples (10 mL) will be drawn from the antecubital vein. After centrifugation and serum separation, the samples will be stored at -75°C until analysis. Nitric o | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Farzizadeh
University of Mohaghegh Ardabili
Outcome results
None listed