Studying the effects of aerobic exercise and vitamin E on depression severity and mental health in women with depressive symptoms

Investigating the Effects of eight weeks Aerobic Training and Vitamin E consumption on depression Severity and Some Mental Health Indicators in Women with Depressive Symptoms

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250403065195N1

Enrollment

Registered

2025-04-28

Start date

2025-04-30

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. Major depressive disorder, single episode, mild

Interventions

Intervention 1: Intervention group: Continuous aerobic exercise, including 3 training sessions per week for 8 weeks. In the first week, the exercises will be performed for 20 minutes at an intensity

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age range 18 to 50 years Resident of Kermanshah city Body mass index (BMI) less than 29.9 kg/m2 Having depressive symptoms (score of 16 or higher on the Center for Epidemiological Studies Depression Scale)

Exclusion criteria

Exclusion criteria: Presence of musculoskeletal abnormalities or disorders Participation in a regular exercise program in the past 6 months Taking supplements with anti-inflammatory properties

Design outcomes

Primary

Measure	Time frame
Change in severity of depression. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Standard questionnaire of the Center for Epidemiological Studies.;Change in quality of life. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Use of the Mental Health Quality of Life (MHQoL) questionnaire.;Change in sleep quality. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Using the Pittsburgh Sleep Quality Questionnaire.;Self-concept review. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Using the Robson Self-Concept Questionnaire.;Change in self-esteem. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Using the Rosenberg Self-Esteem Scale.;Change in memory status. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Using the standard MCS questionnaire (Memory Complaints Scale) to assess memory status.	—

Measure

Time frame

Change in severity of depression. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Standard questionnaire of the Center for Epidemiological Studies.;Change in quality of life. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Use of the Mental Health Quality of Life (MHQoL) questionnaire.;Change in sleep quality. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Using the Pittsburgh Sleep Quality Questionnaire.;Self-concept review. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Using the Robson Self-Concept Questionnaire.;Change in self-esteem. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Using the Rosenberg Self-Esteem Scale.;Change in memory status. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Using the standard MCS questionnaire (Memory Complaints Scale) to assess memory status.

—

Secondary

Measure	Time frame
General fatigue assessment. Timepoint: Before the start of the intervention and 8 weeks after the start of the intervention. Method of measurement: Using the Multidimensional Fatigue Index (MFI) questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEhsan Amiri

The University of Razi

e.amiri@razi.ac.ir+98 83 3845 8428

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026