Methylene blue as identifier of Parathyroid Glands

Investigating the effect of identifying parathyroid glands using methylene blue on reducing hypocalcemia after thyroidectomy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250331065186N1

Enrollment

Registered

2025-06-28

Start date

2025-04-30

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid disease. Disorder of thyroid, unspecified

Interventions

Intervention 1: Intervention Group:In this group, patients will undergo a total thyroidectomy procedure following standard surgical protocols, with the addition of methylene blue as an adjunct to faci

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Thyroidectomy surgery for any reason 2. Over 18 years of age

Exclusion criteria

Exclusion criteria: 1. History of calcium disorders 2. Abnormal calcium before surgery 3. Metastatic cancers 4. Previous history of thyroid surgery

Design outcomes

Primary

Measure	Time frame
Calcium level. Timepoint: One day before and one day after the operation. Method of measurement: automated techniques using COBAS integra reagents (Cobas Integra, Roche Diagnostics, Switzerland).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbbas Alizade

Karaj University of Medical Sciences

Abbas.alz7676@gmail.com+98 26 3350 7042

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026