Surgical site infections following emergency cesarean section.
Conditions
Interventions
Intervention 1: Intervention group: Vaginal douching to chlorhexidine solution
Intervention: Vaginal wash with 0.5% chlorhexidine solution before emergency cesarean section
Dose and amount: 10 mL of 0.5% chlorhexidine solution
Frequency: Once, 30 minutes before the surgical procedure
Duration: Single session prior to surgery
Method of administration: Chlorhexidine solution is instilled into the vagina using a sterile syringe and drained after 5 minutes
Equipment and materials: 10 mL sterile syringe, 0.5% chlorhexidine solution, sterile gloves
Manufacturer: Tehran Shimi Pharmaceutical Company. Intervention 2: Control group: Intervention: Vaginal wash with 10% povidone-iodine solution (Betadine) before emergency cesarean section
Dose and amount: 10 mL of 10% povidone-iodine solution
Method of administration: Povidone-iodine solution is instilled into the vagina using a sterile syringe and drained after 5 minutes
Equipment and materials: 10 mL sterile syringe, 10% povidone-iodine solution, sterile gloves
Manufacturer: Tehran Shimi Pharmaceutical Company.
Sponsors
Sabzevar University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Gestational age between 37 and 42 weeks (term pregnancy) Singleton pregnancy Maternal age = 18 years Need for emergency cesarean section General condition suitable for tolerating the intervention and follow-up
Exclusion criteria
Exclusion criteria: Patients with allergy to povidone-iodine or chlorhexidine Patients with signs of chorioamnionitis or fever during labor, or other signs of infection Active vaginal or genital infection at the time of surgery History of previous infections related to wound or vagina Unstable underlying disease Lack of willingness or ability to sign the informed consent form Inability to follow up after surgery Presence of chorioamnionitis or fever before cesarean section
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fever = 38°C. Timepoint: Days 1, 7, 15, and 30 after cesarean section. Method of measurement: Body temperature measured with a digital thermometer by a trained nurse.;Wound redness. Timepoint: Days 1, 7, 15, and 30 after cesarean section. Method of measurement: Clinical examination by a trained nurse.;Wound swelling. Timepoint: Days 1, 7, 15, and 30 after cesarean section. Method of measurement: Clinical examination by a trained nurse. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNasrin Fazel
Sabzevar University of Medical Sciences
Outcome results
None listed