Type 2 diabetes. Diabetes mellitus due to underlying condition
Conditions
Interventions
Intervention 1: First intervention group: Patients with type 2 diabetes mellitus will be treated with atorvastatin to reduce cholesterol and LDL-C and thereby inhibit microvascular and macrovascular c
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
19 Years to 69 Years
Inclusion criteria
Inclusion criteria: Atorvastatin 40 mg per day and rosuvastatin 20 mg per day are recommended for type 2 diabetic patients who require treatment with this drug. Type 2 diabetic patients should not have used statin drugs before treatment. Type 2 diabetic patients aged 19-69 years and healthy individuals aged 19-69 years. Healthy people visit the laboratory for routine examinations or checkups. Healthy individuals without any specific disease, no history of surgery, with normal lipid and sugar profiles Diabetic patients must have had diabetes for at least 2 years. Not receiving insulin
Exclusion criteria
Exclusion criteria: Women who are pregnant or breastfeeding. People who have an active infection or are infected with hepatitis B, hepatitis C, HIV, or tuberculosis. History of any type of cancer Heart attack within the past 6 months or peripheral coronary artery disease Being treated for a chronic condition that requires steroids, such as prednisone. Smoking and alcohol use Women who take contraceptives. Chronic indigestion and diarrhea, failure of important organs, such as the liver, lungs, kidneys, and brain, as well as anemia and diabetic nephropathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood level of furin. Timepoint: Measuring blood levels of furin before treatment with atorvastatin and rosuvastatin and three months after treatment with them. Method of measurement: ELISA method using ELISA reader.;Blood sugar levels. Timepoint: Measurement of blood sugar indicators before treatment with atorvastatin and rosuvastatin and three months after treatment with them. Method of measurement: Photometric method using an autoanalyzer.;Blood lipid index levels. Timepoint: Measurement of blood lipid indices before treatment with atorvastatin and rosuvastatin and three months after treatment with them. Method of measurement: Photometric method using an autoanalyzer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Nosrati Andevari
Kerman University of Medical Sciences
Outcome results
None listed