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Comparison of different forms of lidocaine on pain intensity and side effects caused by nasogastric tube placement

Comparison of the effectiveness of lidocaine gel, spray and drops on pain intensity and side effects caused by nasogastric tube placement

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250318065126N1
Enrollment
124
Registered
2025-05-17
Start date
2025-07-06
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lidocaine gelLidocaine sprayLidocaine drops Pain intensitySide effectsNasogastric tube (NG tube).

Interventions

Intervention 1: Intervention group 1: Lidocaine gel (using 2.5 ml (equivalent to 50 mg of effective lidocaine) of the gel in the 2% lidocaine tube manufactured by Sina Daru Company, Tehran, each ml of

Sponsors

Gonabad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Informed consent Patients requiring NGT (No. 16) as determined by the treating physician Age 18–60 years Hemodynamically stable condition No clinical harm from a 3–5 minute delay in tube placement

Exclusion criteria

Exclusion criteria: Pregnancy Patient discharge or development of any condition rendering the intervention unfeasible Being on anticoagulant therapy Having a skull base fracture and facial trauma Esophageal trauma, especially in the context of consuming caustic substances Esophageal obstruction, such as a neoplasm or foreign body Having an allergy to lidocaine Pain in the throat, nose, and ears

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: In both the intervention and control groups, measurements will be taken during the intervention, immediately after, and at 5 and 10 minutes following the catheterization procedure. Method of measurement: Pain intensity will be measured using the Visual Analog Scale (VAS).;Nausea (side effect). Timepoint: Side effects will be recorded during the intervention and immediately after the intervention through observation, questioning of the patient and the nurse in charge. Method of measurement: Through observation, questions from the patient and the nurse in charge will be recorded.;Vomiting (side effect). Timepoint: Side effects will be recorded during the intervention and immediately after the intervention through observation, questioning of the patient and the nurse in charge. Method of measurement: Through observation, questions from the patient and the nurse in charge will be recorded.;Cough (side effect). Timepoint: Side effects will be recorded during the intervention and immediately after the intervention through observation, questioning of the patient and the nurse in charge. Method of measurement: Through observation, questions from the patient and the nurse in charge will be recorded.;Epistaxis(side effect). Timepoint: Side effects will be recorded during the intervention and immediately after the intervention through observation, questioning of the patient and the nurse in charge. Method of measurement: Through observation, questions from the patient and the nurse in charge will be recorded.;Pulmonary aspiration (side effects). Timepoint: Side effects will be recorded during the intervention and immediately after the intervention through observation, questioning of the patient and the nurse in charge. Method of measurement: Through observation, questions from the patient and the nurse in charge will be recorded.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTahereh Balochi Bidakhti

Gonabad University of Medical Sciences

tbaloochi@gmail.com+98 51 5722 5027

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026