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A comparative study of the effect of tumescent technique, tumescent technique with added tranexamic acid and saline injection in reducing surgical complications and length of stay in burn injury patients

A comparative study of the effect of tumescent technique, tumescent technique with added tranexamic acid and saline injection in reducing surgical complications and length of stay in burn injury patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250317065110N1
Enrollment
100
Registered
2025-04-28
Start date
2025-04-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn Injury. Burn of third degree of head, face, and neck

Interventions

Intervention 1: tumescent group tumescent: Here is the English translation:---During the surgery, the tumescent technique will be used. This involves the subcutaneous injection of diluted epinephrine

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age between 18-50 years Patients with 10% to 50% burn injuries "Having no underlying disease" or "No pre-existing conditions" The time between the occurrence of the burn injury and the visit to the Imam Musa Kazim Educational and Medical Center should be less than 7 days.

Exclusion criteria

Exclusion criteria: Burns in vulnerable areas such as the face and genitalia Patients taking medications that interfere with coagulation processes

Design outcomes

Primary

MeasureTime frame
Amount of blood lost during surgery. Timepoint: Before and after the intervention. Method of measurement: Number of blood-soaked gauzes.;Occurrence of postoperative bleeding. Timepoint: Before and after the intervention. Method of measurement: Observation and recording in the checklist.;Hemoglobin level before and after surgery. Timepoint: Before and after the intervention. Method of measurement: **Blood test**.;Duration of surgery. Timepoint: Before and after the intervention. Method of measurement: watch.;Amount of blood products transfused. Timepoint: Before and after the intervention. Method of measurement: Observation and recording in the checklist.;Wound culture. Timepoint: Before and after the intervention. Method of measurement: Wound culture test.;Total amount of analgesic medication used during hospitalization. Timepoint: Before and after the intervention. Method of measurement: Observation and recording in the checklist.;Wound preparation for grafting. Timepoint: Before and after the intervention. Method of measurement: Observation and recording in the checklist.;Time from surgery completion to full patient consciousness. Timepoint: Before and after the intervention. Method of measurement: Observation and recording in the checklist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahmood Omranifard

Esfahan University of Medical Sciences

m_omranifard@med.mui.ac.ir+98 31 3345 7670

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026