Prevention.
Conditions
Interventions
Intervention 1: The core training group will perform core stability and strength exercises for 8 weeks, 3 sessions per week. Intervention 2: Intervention group: The NMES group will receive neuromuscul
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
Male
Age
35 Years to 55 Years
Inclusion criteria
Inclusion criteria: Gender: Male Age: 35 to 55 years Good general health (No chronic metabolic, cardiovascular, or neuromuscular diseases) No prior regular core training or NMES usage in the past six months No use of hormonal drugs or metabolism-affecting supplements Ability to attend study sessions and adhere to the research protocol No regular alcohol or tobacco consumption
Exclusion criteria
Exclusion criteria: Presence of metabolic, cardiovascular, or neuromuscular diseases (e.g., diabetes, heart disease, multiple sclerosis). Use of hormonal medications or supplements affecting metabolism (e.g., testosterone, steroids, insulin). History of NMES use in the past six months. Recent surgeries affecting physical activity or muscle function. Presence of implantable electronic devices (e.g., pacemakers) that may interfere with NMES.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome variables include changes in anabolic hormones (testosterone, IGF-1, growth hormone), catabolic hormones (cortisol), related metabolic markers (insulin, ALT, AST, alkaline phosphatase), and sports performance indices (muscle strength, endurance, flexibility, step length and time, symmetry, and dynamic stability in gait). These variables will be measured before and after the intervention. Timepoint: The outcome variables will be measured at two time points: before the intervention (Baseline) and after the intervention period (Post-intervention, week 8). Method of measurement: Anabolic and catabolic hormones (testosterone, IGF-1, growth hormone, cortisol, insulin): Blood samples will be collected in a fasting state and analyzed using Chemiluminescent Immunoassay (CLIA). Liver enzymes (ALT, AST) and alkaline phosphatase: Measured using biochemical enzymatic methods? Sports performance:Muscle strength and endurance using a handheld dynamometer and standard endurance tests. Flexibility using the Sit and Reach Test. Step length, step time, symmetry, and dynamic stability in gait will be assessed using motion analysis and gait assessment systems? Quality of Life Questionnaire (English):To assess quality of life, the Short Form Health Survey (SF-36) will be used. This questionnaire consists of 36 questions evaluating various aspects of physical and mental health. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKhosro Jalali Dehkordi
Islamic Azad University
Outcome results
None listed