Studying the effect of Exemestane on changes in visual evoked potentials in patients with breast cancer

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250314065067N1

Enrollment

Registered

2025-04-20

Start date

2026-03-21

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the effect of Exemestane on the optic nerve by visual evoked potential technique.

Interventions

Intervention 1: Intervention group: The patients will receive exemestane at a dose of 25 mg per day for 6 months. Intervention 2: Control group: The control group will not receive medication.

Eligibility

Sex/Gender

Female

Age

35 Years to 60 Years

Inclusion criteria

Inclusion criteria: women with age of 35 to 60 years old breast cancer diagnosis

Exclusion criteria

Exclusion criteria: Having hereditary or generalized retinal dystrophy

Design outcomes

Primary

Measure	Time frame
Changes in the amplitude of the p100 wave. Timepoint: 6 months after the start of the intervention. Method of measurement: The subject is positioned 3 meters from the monitor and electrodes are attached to specific areas of the head (visual cortex, ear, and forehead) using a special gel and adhesive. Visual signals are received by the electrodes and transmitted to a computer via an analog-to-digital converter to record and analyze visual responses to Flash and Pattern patterns. Changes in the amplitude of the p100 wave will be examined.	—

Measure

Time frame

Changes in the amplitude of the p100 wave. Timepoint: 6 months after the start of the intervention. Method of measurement: The subject is positioned 3 meters from the monitor and electrodes are attached to specific areas of the head (visual cortex, ear, and forehead) using a special gel and adhesive. Visual signals are received by the electrodes and transmitted to a computer via an analog-to-digital converter to record and analyze visual responses to Flash and Pattern patterns. Changes in the amplitude of the p100 wave will be examined.

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Countries

Iran (Islamic Republic of)

Contacts

Public Contactmehrsa mennati

Islamic Azad University

marymenati@gmail.com+98 21 4412 9079

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026