Evaluation of the effect of an artificial saliva produced from aqueous extract of Okra ( Abelmoschus Esculentus) on the xerostomia symptoms in diabetic patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250311065040N1

Enrollment

Registered

2025-04-22

Start date

2025-05-05

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Xerostomia. Disturbances of salivary secretion

Interventions

Intervention 1: Intervention group: People in this group, including 40 patients, will rinse their mouths with 2 ml of aqueous extract of okra fruit (30 g sorbitol, 11.7 g aqueous extract of okra, 804

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Be between the ages of 18 and 65 years old Patients must have dry mouth, based on the Fox questionnaire with at least a positive response to 4 of the 9 questions on the questionnaire Diabetes based on diabetes diagnosis criteria

Exclusion criteria

Exclusion criteria: Pregnancy Taking medications that reduce salivation Use of other artificial saliva products History of autoimmune diseases History of pneumonia Presence of oral or perioral lesions

Design outcomes

Primary

Measure	Time frame
Score obtained on the Fox questionnaire. Timepoint: Days 0 and 14 of the study. Method of measurement: Fox Dry Mouth Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Shirmehenji

Birjand University of Medical Sciences

h.shirmehenji@bums.ac.ir+98 56 3238 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026