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Studying the effect of vitamin C and erythropoietin on brain contogenesis

Investigating the effect of intravenous vitamin C and erythropoietin as a combination in increasing the level of consciousness of patients with cerebral contusion hospitalized in the intensive care unit (ICU)fvv

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250311065036N1
Enrollment
90
Registered
2025-05-03
Start date
2025-05-10
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral contusion. Focal traumatic brain injury

Interventions

Intervention 1: Intervention group: In the first group, patients will undergo a combined vitamin C and erythropoietin treatment protocol. In the first group, erythropoietin will be injected into the p

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with frontal, temporal, and parietal lobe contusions without skull base fractures

Exclusion criteria

Exclusion criteria: Patients under 15 years of age or over 70 years of age It is not possible to obtain informed consent from the legal representative or their family members. Or have other major organ injuries such as burns, abdominal injuries, or chest injuries Those with previous chronic diseases such as chronic renal failure, iron deficiency anemia, coronary heart disease, severe liver disease, or G6PD deficiency will be excluded from the study. Have hemoglobin above 13 grams per deciliter or hematocrit above 50 percent. Patients with a history of DVT

Design outcomes

Primary

MeasureTime frame
The Glasgow Coma Scale (GCS) is a measure for determining the depth and severity of decreased level of consciousness or coma in people over the age of 5. Timepoint: At the beginning of the study and 28 days later. Method of measurement: Using GCS score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahabadin Savari

Ardabil University of Medical Sciences

Savari.shahabadin@yahoo.com+98 45 3352 2310

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026