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Effect of carboxytherapy in treatment of psoriasis

Comparison of efficacy of carboxytherapy and topical triamcinolone acetonide 0.1% in the treatment of plaque_type psoriasis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250310065010N1
Enrollment
28
Registered
2025-03-25
Start date
2025-04-04
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis. Psoriasis

Interventions

Intervention 1: Intervention group : In our patients in the intervention group, carboxytherapy is performed by injecting 1 CC of CO2 gas into the lesion at a distance of 2 cm using the MEDAION carboxy

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age > 18 Both sex Localized plaque psoriasis (involvement of less than 30% of the body surface) Disease duration less than 5 years Presence of involvement of organs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The variable under study is actually the clinical response to treatment of psoriasis and is evaluated based on clinical criteria such as size, erythema, induration, scaling, recurrence, and patient satisfaction. Timepoint: Clinical examination and high-resolution digital radiography will be used to assess the results at time 0, before each carboxytherapy session, and 2 weeks after the last session. In addition, patients will be evaluated for lesion recurrence 1 month after the last evaluation session. Therefore, patients will be followed for 14 weeks from the time of inclusion in the study. Method of measurement: Various tools are used for clinical studies, including: the investigator's general assessment criteria, which indicate the outcome of the response to treatment from the perspective of the study researcher, the symptom score criteria, which is determined by symptoms such as erythema, induration, and scaling, a visual analogue scale to measure pain, assessing patient satisfaction based on a 10-point scale, and assessing recurrence based on the tables mentioned.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Mansouri

Arak University of Medical Sciences

alimansour8082@gmail.com+98 86 3497 9295

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026