Multiple sclerosis. Multiple sclerosis
Conditions
Interventions
Intervention 1: Control Group: Only placebo will be received! An active placebo with 5% coffee, essence, and chemicals, also prepared with a flavor similar to coffee, will be delivered to the placebo
the exercise intervention will be implemented for 8 weeks with a frequency of 3 sessions per week (on even days to avoid excessive fatigue). Each session will last approximately 30-35 minutes, includi
a total of 32 days) for eight weeks.To prepare the suspension, the daily dose was calculated based on each individual's weight and packaged in 250-milligram bottles for delivery to the subjects.Ingred
Sponsors
University of Birjand
Eligibility
Sex/Gender
All
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Age range 20 to55 years Not taking amantadine and dalfira drugs EDSS score =5.4 points (4.5-1) Patient approval from the doctor Not receiving other rehabilitation activities during the study period Completed the informed consent form Suffering from relapsing-remitting type No skin sensitivity or flushing due to the use of the ingredients in Qavoot
Exclusion criteria
Exclusion criteria: Personal dissatisfaction Injury while performing the exercise program Participation in organized exercise and rehabilitation programs other than the exercise program of the present study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle Synergy Index (Muscle Synergy Index or the number/structure of muscle synergies) calculated from electromyography (EMG) signals during walking. Timepoint: Before the start of the intervention and eight weeks after the intervention. Method of measurement: Extraction of muscle synergies using Non-negative Matrix Factorization (NMF) analysis or similar methods on sEMG data of muscles involved in the gait cycle (e.g. Quadriceps, Hamstrings, Gastrocnemius, Tibialis Anterior).The number of synergies, the contribution of each synergy (muscle weight per synergy), or the amount of variance explained (VAF) by the synergies using Matlab software.;Sleep Quality Index. Timepoint: Before the start of the intervention and eight weeks after the intervention. Method of measurement: Pittsburgh Sleep Quality Index.;Quality of life index. Timepoint: Before the start of the intervention and eight weeks after the intervention. Method of measurement: (MSQoL-54).;Timed Up and Go. Timepoint: Before the start of the intervention and eight weeks after the intervention. Method of measurement: Measuring round trip time using a stopwatch.;Timed 25-Foot Walk - T25FW. Timepoint: Before the start of the intervention and eight weeks after the intervention. Method of measurement: Measuring round trip time using a stopwatch. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life score. Timepoint: Before the intervention and eight weeks later. Method of measurement: Quality of life questionnaire.;Sleep quality score. Timepoint: Before the intervention and eight weeks later. Method of measurement: sleep quality questionnaire.;25-foot and TUG test. Timepoint: Before the intervention and eight weeks later. Method of measurement: Measuring round trip time. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyyed mojtaba Hosseini
University of Birjand
Outcome results
None listed