Investigation of airway irritation in patients undergoing general anesthesia with propofol and thiopental sodium.
Conditions
Interventions
Intervention 1: Intervention group: Intravenous administration of propofol at a dose of 2-2.5 mg/kg for anesthesia induction,with a concentration of 1% (10 mg/mL), administered intravenously for vario
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 60 years Requirement for general anesthesia for surgery Provision of written informed consent to participate in the study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The level of airway irritation, including changes in respiratory rate, heart rate, cough and blood pressure fluctuations, with an increase above 140/90 or a decrease below 90/60. Timepoint: Vital signs assessment at the beginning of the study (before the intervention) and at 1, 2, and 6 hours after anesthesia induction. Method of measurement: Airway Irritation is assessed by observing and recording coughing, dyspnea, and oxygen desaturation at 1, 2, and 6 hours post-anesthesia through clinical observations, pulse oximetry (Pulse Oximeter), and vital signs monitoring.Respiratory Rate is measured by counting the number of breaths per minute using a vital signs monitor.Heart Rate is recorded as the number of beats per minute using electrocardiography (ECG) and a cardiac monitor.Blood Pressure is measured by assessing systolic and diastolic blood pressure at predefined time points using an automatic sphygmomanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Mahdavi Afshar
Islamic Azad University
Outcome results
None listed